Enteric Film Coating System
Description
The Enteric Film Coating System is designed specifically for controlled, delayed-release formulations, protecting active pharmaceutical ingredients (APIs) from the acidic environment of the stomach and allowing for their release in the more alkaline environment of the small intestine. This system is commonly used for drugs that require targeted release, such as those that may irritate the stomach lining or are unstable in gastric fluids. The enteric coating ensures that the active ingredients remain intact and are only released after passing through the stomach, offering therapeutic benefits that cannot be achieved with traditional coatings.
The system is ideal for formulations that require protection from gastric juices, allowing for a controlled, site-specific release of the active ingredient. It is used in both aqueous and non-aqueous systems and can be applied to a variety of dosage forms, including tablets and pellets. Enteric coatings can also help reduce the potential for side effects like gastric irritation, making it an essential option for many drug formulations.
Benefits
The enteric coating ensures that the active pharmaceutical ingredient is not released in the stomach but rather in the more alkaline environment of the small intestine, where absorption is optimal.
Enteric coatings help prevent irritation or discomfort in the stomach lining by allowing the tablet or capsule to bypass the stomach and dissolve in the intestine. This is particularly beneficial for drugs that can cause nausea, vomiting, or other gastrointestinal issues when taken orally.
This coating system helps protect drugs that are unstable in the acidic environment of the stomach, ensuring that they remain effective by releasing them in a more stable, alkaline environment in the small intestine.
Applications
- Gastrointestinal Medications
- Enzyme Tablets
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